购物车
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021-54845833/15800441009
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Fusion protein corresponding to a region derived from C terminal 300 amino acids of humanFASTK |
技术规格
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Full name: |
fas-activated serine/threonine kinase |
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Synonyms: |
FAST |
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Swissprot: |
Q14296 |
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Gene Accession: |
BC000377 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. |
