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021-54888888/15800441009
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Background: |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous ne金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingorking strands in the ou金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This gene encodes a component of tight junction strands, which is a member of the claudin family. The protein is an integral membrane protein and is one of the entry cofactors for hepatitis C virus. The gene methylation may be involved in esophageal tumorigenesis. This gene is adjacent to another family member CLDN9 on chromosome 16. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CLDN6 |
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Immunogen: |
Synthetic peptide of human CLDN6 |
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Full name: |
claudin 6 |
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SwissProt: |
P56747 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer and human esophagus cancer |
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IHC Recommend dilution: |
25-100 |
