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中文名称：NAE1抗原（重组蛋白）
英文名称： NAE1 Antigen (Recombinant Protein)
别 名： HPP1; ula-1; APPBP1; A-116A10.1
储 存： 冷冻（-20℃）
相关类别 ：抗原
概 述：
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Fusion protein corresponding to C terminal 250 amino acids of human NAE1 |
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Full name: |
NEDD8 activating enzyme E1 subunit 1 |
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Synonyms: |
HPP1; ula-1; APPBP1; A-116A10.1 |
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Swissprot: |
Q13564 |
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Gene Accession: |
BC000480 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
