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中文名称：UBQLN1抗原（重组蛋白）
英文名称： UBQLN1 Antigen (Recombinant Protein)
别 名： DA41; DSK2; UBQN; XDRP1; PLIC-1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to C terminal 250 amino acids of human UBQLN1 |
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Full name: |
ubiquilin 1 |
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Synonyms: |
DA41; DSK2; UBQN; XDRP1; PLIC-1 |
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Swissprot: |
Q9UMX0 |
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Gene Accession: |
BC039294 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. |
