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中文名称：OLR1抗原（重组蛋白）
英文名称： OLR1 Antigen (Recombinant Protein)
别 名： LOX1; LOXIN; SLOX1; CLEC8A; SCARE1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 58-273 amino acids of human OLR1 |
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Full name: |
oxidized low density lipoprotein (lectin-like) receptor 1 |
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Synonyms: |
LOX1; LOXIN; SLOX1; CLEC8A; SCARE1 |
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Swissprot: |
P78380 |
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Gene Accession: |
BC022295 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants. |
