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中文名称：PTK2抗原（重组蛋白）
英文名称： PTK2 Antigen (Recombinant Protein)
别 名： FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to C terminal 250 amino acids of human PTK2 |
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Full name: |
protein tyrosine kinase 2 |
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Synonyms: |
FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK |
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Swissprot: |
Q05397 |
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Gene Accession: |
BC028733 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene, but the full-length natures of only three of them have been determined. |
