Full name: |
NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa |
Synonyms: |
TYKY; CI-23k; CI23KD |
Swissprot: |
O00217 |
Gene Accession: |
BC119754 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, or Complex I, a multimeric enzyme of the respiratory chain responsible for NADH oxidation, ubiquinone reduction, and the ejection of protons from mitochondria. The encoded protein is involved in the binding of 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo of the six to eight iron-sulfur clusters of Complex I and, as such, is required in the electron transfer process. Mutations in this gene have been associated with Leigh syndrome. |