中文名称:CASP7抗原(重组蛋白)
英文名称:CASP7 Antigen (Recombinant Protein)
储 存:冷冻(-20℃)
相关类别:抗原
概述
Fusion protein corresponding to a region derived from 207-303 amino acids of human CASP7 |
技术规格
Full name: |
caspase 7, apoptosis-related cysteine peptidase |
Synonyms: |
MCH3; CMH-1; LICE2; CASP-7; ICE-LAP3 |
Swissprot: |
P55210 |
Gene Accession: |
BC015799 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |