金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting

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    • OTUB1抗原(重组蛋白)

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      • 品牌 : 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物
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    中文名称: OTUB1抗原(重组蛋白)

    英文名称: OTUB1 Antigen (Recombinant Protein)

    别       名: OTU deubiquitinase, ubiquitin aldehyde binding 1; OTB1; OTU1; HSPC263

    储       存: 冷冻(-20℃)

    相关类别: 抗原

    概述

    Fusion protein corresponding to a region derived from 80-271 amino acids of human OTUB1

    技术规格

    Full name:

    OTU deubiquitinase, ubiquitin aldehyde binding 1

    Synonyms:

    OTB1; OTU1; HSPC263

    Swissprot:

    Q96FW1

    Gene Accession:

    BC007519

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth.

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