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Background: |
∫-defensins (also designated BDs, or hBDs in human) are small cationic peptides with broad-spectrum antimicrobial activity against a variety of enveloped viruses, fungi and bacteria. Produced in mucosal epithelia and neutrophils of several species, ∫-defensins are developmentally regulated. The family of ∫-defensin proteins share a common defensin-motif that is characterized by multiple cysteine residues and a highly conserved tertiary structure. Besides playing a significant role in host immune defense, many ∫-defensins also are involved in sperm maturation and capacitation. ∫-defensin 32, also known as ∫-defensin 132, is a 95 amino acid secreted protein that most likely contains a signal peptide sequence that requires cleavage by proteolytic enzymes in order to become biologically active. |
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Applications: |
WB |
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Name of antibody: |
DEFB132 |
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Immunogen: |
Fusion protein of human DEFB132 |
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Full name: |
defensin, beta 132 |
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Synonyms： |
DEFB32; UNQ827 |
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SwissProt: |
Q7Z7B7 |
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WB Predicted band size: |
11 kDa |
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WB Positive control: |
Testis tissue |
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WB Recommended dilution: |
500-2000 |
