购物车
帮助
021-54888888/15800441009
概 述
|
Full name: |
inosine triphosphatase (nucleoside triphosphate pyrophosphatase) |
|
Synonyms: |
My049; C20orf37; dJ794I6.3; HLC14-06-P |
|
Swissprot: |
Q9BY32 |
|
Gene Accession: |
BC010138 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
|
Tags: |
His tag C-Terminus, GST tag N-Terminus |
|
Background: |
This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants. |
