Name: RARB抗原（重组蛋白）
Brand: 通蔚生物

中文名称： RARB抗原（重组蛋白）

英文名称： RARB Antigen (Recombinant Protein)

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to a region derived from 200-419 amino acids of human RARB

技术规格

Full name:	retinoic acid receptor, beta
Synonyms:	HAP; RRB2; NR1B2
Swissprot:	P10826
Gene Accession:	BC060794
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.

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