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Background: |
Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Finally, peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
F2 |
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Immunogen: |
Synthetic peptide of humanF2 |
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Full name: |
coagulation factor II (thrombin) |
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Synonyms： |
PT; THPH1; RPRGL2 |
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SwissProt: |
P00734 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human prostate cancer |
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IHC Recommend dilution: |
25-100 |
