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    • SIAH1 抗原(重组蛋白)

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      • 品牌 : 通蔚生物
      • 目录号 : TW4920
      • 应用 : 仅供科研使用
      • 货期 : 现货
      • 规格 :100ug
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    中文名称: SIAH1 抗原(重组蛋白)

    英文名称: SIAH1 Antigen (Recombinant Protein)

    别     名: siah E3 ubiquitin protein ligase 1; SIAH1A

    储     存:
    冷冻(-20℃)

    相关类别:抗原

    概      述

    Fusion protein corresponding to a region derived from 1-282 amino acids of human SIAH1

    技术规格

    Full name:

    siah E3 ubiquitin protein ligase 1

    Synonyms:

    SIAH1A

    Swissprot:

    Q8IUQ4

    Gene Accession:

    BC035562

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008]


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