中文名称:CASP9抗原(重组蛋白)
英文名称:CASP9 Antigen (Recombinant Protein)
储 存:冷冻(-20℃)
相关类别:抗原
概述
Fusion protein corresponding to a region derived from 139-389 amino acids of human CASP9 |
Full name: |
Caspase-9 |
Synonyms: |
MCH6, APAF3, APAF-3, PPP1R56, ICE-LAP6 |
Swissprot: |
P55211 |
Gene Accession: |
BC002452 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo transcript variants which encode different isoforms. |