中文名称：HSD3B7 抗原（重组蛋白）

英文名称：HSD3B7 Antigen (Recombinant Protein)

别名：hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; CBAS1; PFIC4; SDR11E3

储存：冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to N terminal 178 amino acids of human HSD3B7

技术规格

Full name:

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7

Synonyms:

CBAS1; PFIC4; SDR11E3

Swissprot:

Q9H2F3

Gene Accession:

BC004929

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.

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HSD3B7 抗原（重组蛋白）说明书
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ELISA试剂盒

PCR试剂盒

生化试剂盒

细胞系

细胞库

基础培养基

完全培养基

原代细胞

细胞专用培养基

菌株

生化试剂

病理染色液

科研抗体

标准品

血清

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HSD3B7 抗原（重组蛋白）

Full name:	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
Synonyms:	CBAS1; PFIC4; SDR11E3
Swissprot:	Q9H2F3
Gene Accession:	BC004929
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.