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021-54888888/15800441009
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Background: |
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous ne金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingorking strands in the ou金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CLDN1 |
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Immunogen: |
Synthetic peptide of human CLDN1 |
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Full name: |
claudin 1 |
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Synonyms： |
CLD1, SEMP1, ILVASC |
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SwissProt: |
O95832 |
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ELISA Recommended dilution: |
1000-10000 |
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IHC positive control: |
Human esophagus cancer and Human cervical cancer |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
Hela cells |
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WB Recommended dilution: |
1000-3000 |
