金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting


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  • DIABLO抗原(重组蛋白)

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    • 品牌 : 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物
    • 目录号 : TW16714
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中文名称: DIABLO抗原(重组蛋白)

英文名称: DIABLO Antigen (Recombinant Protein)

别      名: SMAC; SMAC3; DFNA64; DIABLO-S

储      存: 冷冻(-20℃)

相关类别: 抗原

概述

Fusion protein corresponding to a region derived from 56-239 amino acids of human DIABLO

技术规格

Full name:

Diablo, IAP-binding mitochondrial protein

Synonyms:

SMAC; SMAC3; DFNA64; DIABLO-S

Swissprot:

Q9NR28

Gene Accession:

BC011909

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and it moderates the caspase inhibition of IAPs. Multiple polyadenylation sites have been found for this gene. Four alternatively spliced transcript variants have been described for this gene, with 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo of them encoding different isoforms and the other 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo probably not encoding a protein. Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes. Isoform 3 is ubiquitously expressed.

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