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中文名称：BGN抗原（重组蛋白）
英文名称： BGN Antigen (Recombinant Protein)
别 名： PGI; DSPG1; PG-S1; SLRR1A
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 38-338 amino acids of human BGN |
|
Full name: |
biglycan |
|
Synonyms: |
PGI; DSPG1; PG-S1; SLRR1A |
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Swissprot: |
P21810 |
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Gene Accession: |
BC002416 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. |
