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中文名称： 兔抗NOTCH1多克隆抗体
英文名称： Anti-NOTCH1 rabbit polyclonal antibody
别 名： hN1, TAN1
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： NOTCH1
反应种属： Human, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling ne金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingork is an evolutionarily conserved intercellular signaling pathway which regulates interactions be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi ne金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingork, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play multiple roles during development. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
NOTCH1 |
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Immunogen: |
Synthetic peptide of human NOTCH1 |
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Full name: |
Notch 1 |
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Synonyms： |
hN1, TAN1 |
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SwissProt: |
P46531 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human cervical cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
273 kDa |
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WB Positive control: |
HT-29 cells |
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WB Recommended dilution: |
500-2000 |
