购物车
帮助
021-54845833/15800441009
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Background: |
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
FSCN1 |
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Immunogen: |
Fusion protein of human FSCN1 |
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Full name: |
fascin actin-bundling protein 1 |
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Synonyms: |
HSN; SNL; p55; FAN1 |
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SwissProt: |
Q16658 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human cervical cancer and Human ovarian cancer |
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IHC Recommend dilution: |
25-100 |
