中文名称:CASP6抗原(重组蛋白)
英文名称:CASP6 Antigen (Recombinant Protein)
储 存:冷冻(-20℃)
相关类别:抗原
概述
Fusion protein corresponding to a region derived from 66-221 amino acids of human CASP6 |
技术规格
Full name: |
Caspase 6, apoptosis-related cysteine peptidase |
Synonyms: |
MCH2 |
Swissprot: |
P55212 |
Gene Accession: |
BC000305 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo transcript variants that encode different isoforms. |