中文名称:DNAJB1抗原(重组蛋白)
英文名称: DNAJB1 Antigen (Recombinant Protein)
别 名: Hdj1; Sis1; HSPF1; Hsp40; RSPH16B
储 存: 冷冻(-20℃)
相关类别: 抗原
概 述:
Fusion protein corresponding to C terminal 250 amino acids of human DNAJB1 |
Full name: |
DnaJ (Hsp40) homolog, subfamily B, member 1 |
Synonyms: |
Hdj1; Sis1; HSPF1; Hsp40; RSPH16B |
Swissprot: |
P25685 |
Gene Accession: |
BC002352 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene. Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. |